DEXI

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DEXI RNA expression is significantly associated with the go_rna of many other GO terms, with 3,115 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DEXI-associated GO terms across cancer lineages are Regulation of Golgi inheritance, Symbiont-mediated disruption of host cell PML body, and Multi-pass transmembrane protein insertion into ER membrane. Each is linked with DEXI in more than 13 cancer types. Because this analysis shows association rather than direction, both DEXI-to-partner and partner-to-DEXI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Golgi inheritance grouped by DEXI-low versus DEXI-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEXI→partner) and Y-score (partner→DEXI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINERegulation of Golgi inheritance →+0.133+0.672<.001<.001314
OVARYSymbiont-mediated disruption of host cell PML body →+0.086+0.547<.001<.001313
STOMACHMulti-pass transmembrane protein insertion into ER membrane →+0.133+0.470.007.007212
BREASTNegative regulation of autophagosome maturation →+0.088+0.457<.001<.001212
OVARYRegulation of autophagosome maturation →+0.091+0.776<.001<.001311
LARGE_INTESTINEPositive regulation of autophagy of mitochondrion →+0.098+0.571<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,115 associations by consensus.

Regulation of Golgi inheritance by DEXI expression — LARGE_INTESTINE

Box plot of Regulation of Golgi inheritance in DEXI-low vs DEXI-high samples in LARGE_INTESTINE.

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Exploration