DET1

Across TCGA patient cohorts, DET1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,422 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DET1-associated proteins across cancer lineages are HDGFL3, GABPA, and ANP32A. Each is linked with DET1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DET1-to-partner and partner-to-DET1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DET1 versus HDGFL3 in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DET1→partner) and Y-score (partner→DET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.633	+0.427	<.001	<.001	3	7
GBM	GABPA →	+0.236	+0.292	<.001	<.001	3	6
BRCA	ANP32A →	+0.330	+0.393	<.001	<.001	3	6
BRCA	LUM →	+0.816	+0.366	<.001	<.001	3	5
HNSC	SPAG9_S332 →	-0.889	-0.627	<.001	<.001	3	5
CCRCC	SSC5D →	+0.665	+0.281	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,422 associations by consensus.

DET1 vs HDGFL3 — BRCA

Explore this scatter interactively →