DET1

Across TCGA patient cohorts, DET1 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,183 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DET1-associated proteins across cancer lineages are TMCC2_S126, CCDC115, and CCNDBP1. Each is linked with DET1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DET1-to-partner and partner-to-DET1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DET1 versus TMCC2_S126 in GBM, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DET1→partner) and Y-score (partner→DET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMCC2_S126 →	+1.955	+0.460	.001	.004	3	1
GBM	CCDC115 →	-0.329	-0.448	.003	.006	2	1
GBM	CCNDBP1 →	-0.736	-0.448	.004	.006	2	1
GBM	COLEC11 →	-0.493	-0.535	.004	.008	2	1
GBM	DAB2_S464 →	-1.125	-0.448	.005	.006	2	1
GBM	ACAP1_T739 →	-1.516	-0.600	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,183 associations by consensus.

DET1 vs TMCC2_S126 — GBM

Explore this scatter interactively →