DERL3

Across TCGA patient cohorts, DERL3 RNA expression is significantly associated with the RNA expression of many other genes, with 13,179 significant associations in total. ACC shows the largest number of these associations.

The most reproducible DERL3-associated genes across cancer lineages are POU2AF1, PIM2, and IGLV1-51. Each is linked with DERL3 in more than 30 cancer types. Because this analysis shows association rather than direction, both DERL3-to-partner and partner-to-DERL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DERL3 versus POU2AF1 in CHOL, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DERL3→partner) and Y-score (partner→DERL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	POU2AF1 →	+2.389	+2.040	<.001	.001	3	31
HNSC	PIM2 →	+1.797	+2.291	<.001	<.001	3	30
HNSC	IGLV1-51 →	+3.859	+2.209	<.001	<.001	3	30
CHOL	JCHAIN →	+4.508	+2.170	<.001	.001	3	29
CHOL	MZB1 →	+3.553	+2.305	<.001	.003	3	29
SKCM	IGLV1-40 →	+4.471	+1.966	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,179 associations by consensus.

DERL3 vs POU2AF1 — CHOL

Explore this scatter interactively →