DERL3

Across TCGA patient cohorts, DERL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,231 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DERL3-associated proteins across cancer lineages are MZB1, CD38, and CORO1A. Each is linked with DERL3 in more than 8 cancer types. Because this analysis shows association rather than direction, both DERL3-to-partner and partner-to-DERL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DERL3 versus MZB1 in OV, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DERL3→partner) and Y-score (partner→DERL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MZB1 →	+1.108	+0.733	<.001	<.001	3	9
LSCC	CD38 →	+1.014	+1.181	<.001	<.001	3	9
OV	CORO1A →	+0.748	+0.930	<.001	<.001	3	8
BRCA	HCLS1 →	+0.452	+0.788	<.001	<.001	3	8
OV	SASH3 →	+0.564	+0.889	.002	<.001	3	8
LSCC	SEC11C →	+1.372	+1.297	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,231 associations by consensus.

DERL3 vs MZB1 — OV

Explore this scatter interactively →