DERL3

Across TCGA patient cohorts, DERL3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,638 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DERL3-associated genes across cancer lineages are PIM2, CD79A, and FCRL5. Each is linked with DERL3 in more than 7 cancer types. Because this analysis shows association rather than direction, both DERL3-to-partner and partner-to-DERL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DERL3 versus PIM2 in UCEC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DERL3→partner) and Y-score (partner→DERL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIM2 →	+1.776	+1.326	<.001	.001	3	8
UCEC	CD79A →	+2.341	+1.216	<.001	.003	3	8
UCEC	FCRL5 →	+2.053	+1.326	.001	.002	3	8
OV	IGLC2 →	+3.531	+1.096	<.001	<.001	3	8
UCEC	IGKV1-16 →	+4.171	+1.036	.004	.005	3	8
UCEC	SLAMF7 →	+2.486	+1.446	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,638 associations by consensus.

DERL3 vs PIM2 — UCEC

Explore this scatter interactively →