DERL3

Across TCGA cell cohorts, DERL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,336 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DERL3-associated GO terms across cancer lineages are Zymosterol metabolic process, Zymosterol biosynthetic process, and Isopentenyl diphosphate metabolic process. Each is linked with DERL3 in more than 6 cancer types. Because this analysis shows association rather than direction, both DERL3-to-partner and partner-to-DERL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zymosterol metabolic process grouped by DERL3-low versus DERL3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DERL3→partner) and Y-score (partner→DERL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Zymosterol metabolic process →	+0.128	+1.063	<.001	<.001	3	7
PANCREAS	Zymosterol biosynthetic process →	+0.128	+1.063	<.001	<.001	3	7
PANCREAS	Isopentenyl diphosphate metabolic process →	+0.149	+1.045	<.001	<.001	3	7
PANCREAS	Isopentenyl diphosphate biosynthetic process →	+0.149	+1.045	<.001	<.001	3	7
URINARY_TRACT	PML body organization →	+0.141	+0.834	<.001	.002	3	6
LUNG_SCLC	Isopentenyl diphosphate biosynthetic process, mevalonate pathway →	+0.143	+1.543	.009	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,336 associations by consensus.

Zymosterol metabolic process by DERL3 expression — PANCREAS

Explore this box plot interactively →