DERL1

Across TCGA patient cohorts, DERL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,289 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DERL1-associated proteins across cancer lineages are YTHDF3, ATAD2, and AGO2. Each is linked with DERL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DERL1-to-partner and partner-to-DERL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DERL1 versus YTHDF3 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DERL1→partner) and Y-score (partner→DERL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YTHDF3 →	+0.310	+0.583	.001	<.001	3	7
OV	ATAD2 →	+0.666	+0.599	<.001	<.001	3	6
OV	AGO2 →	+0.368	+0.676	<.001	<.001	3	6
COAD	NUDCD1 →	+0.398	+0.413	<.001	<.001	3	6
LSCC	TATDN1 →	+0.355	+0.305	<.001	<.001	3	5
CCRCC	BPNT2 →	+0.460	+0.467	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,289 associations by consensus.

DERL1 vs YTHDF3 — OV

Explore this scatter interactively →