DEPTOR

Across TCGA patient cohorts, DEPTOR RNA expression is significantly associated with the protein abundance of many other proteins, with 21,233 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DEPTOR-associated proteins across cancer lineages are DEPTOR_S265, DEPTOR_S260, and DDAH1. Each is linked with DEPTOR in more than 9 cancer types. Because this analysis shows association rather than direction, both DEPTOR-to-partner and partner-to-DEPTOR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPTOR versus DEPTOR_S265 in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPTOR→partner) and Y-score (partner→DEPTOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DEPTOR_S265 →	+0.910	+0.878	<.001	<.001	3	10
LUAD	DEPTOR_S260 →	+0.977	+0.826	<.001	<.001	3	8
UCEC	DDAH1 →	+0.628	+0.906	<.001	<.001	3	6
BRCA	FUCA1 →	+0.740	+1.220	<.001	<.001	3	6
BRCA	DEPTOR_S279 →	+0.939	+1.339	<.001	<.001	3	6
LUAD	SELENBP1 →	+0.593	+0.510	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,233 associations by consensus.

DEPTOR vs DEPTOR_S265 — LSCC

Explore this scatter interactively →