DEPTOR

Across TCGA patient cohorts, DEPTOR protein abundance is significantly associated with the RNA expression of many other genes, with 16,471 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DEPTOR-associated genes across cancer lineages are RNA5SP277, SYBU, and COL21A1. Each is linked with DEPTOR in more than 6 cancer types. Because this analysis shows association rather than direction, both DEPTOR-to-partner and partner-to-DEPTOR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPTOR versus RNA5SP277 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPTOR→partner) and Y-score (partner→DEPTOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNA5SP277 →	+1.151	+0.718	<.001	<.001	3	7
BRCA	SYBU →	+1.284	+0.375	<.001	<.001	3	6
UCEC	COL21A1 →	+1.875	+0.510	<.001	<.001	3	6
LSCC	SELENBP1 →	+1.167	+0.442	.003	<.001	3	6
OV	GJB1 →	+1.497	+0.398	<.001	<.001	3	6
LUAD	SLC1A7 →	+1.776	+0.407	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,471 associations by consensus.

DEPTOR vs RNA5SP277 — GBM

Explore this scatter interactively →