DEPTOR

Across TCGA cell cohorts, DEPTOR RNA expression is significantly associated with the go_rna of many other GO terms, with 5,050 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DEPTOR-associated GO terms across cancer lineages are Blood coagulation, intrinsic pathway, Response to platinum ion, and Dentinogenesis. Each is linked with DEPTOR in more than 10 cancer types. Because this analysis shows association rather than direction, both DEPTOR-to-partner and partner-to-DEPTOR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, intrinsic pathway grouped by DEPTOR-low versus DEPTOR-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPTOR→partner) and Y-score (partner→DEPTOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Blood coagulation, intrinsic pathway →	-0.295	-1.828	.008	.004	2	11
BREAST	Response to platinum ion →	+0.124	+1.722	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Dentinogenesis →	-1.906	-1.614	.001	.001	3	9
STOMACH	Fibrinolysis →	-1.701	-2.148	<.001	<.001	3	9
KIDNEY	Regulation of myoblast fusion →	+0.080	+1.498	.002	.003	3	9
LUNG_NSCLC_LUAD	Cellular detoxification →	+0.076	+0.977	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,050 associations by consensus.

Blood coagulation, intrinsic pathway by DEPTOR expression — STOMACH

Explore this box plot interactively →