DEPDC7

Across TCGA patient cohorts, DEPDC7 protein abundance is significantly associated with the RNA expression of many other genes, with 1,041 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DEPDC7-associated genes across cancer lineages are MAPK1, SEZ6L, and C20orf27. Each is linked with DEPDC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEPDC7-to-partner and partner-to-DEPDC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPDC7 versus MAPK1 in CCRCC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC7→partner) and Y-score (partner→DEPDC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MAPK1 →	+0.439	+0.359	.002	.004	3	1
CCRCC	SEZ6L →	-0.061	-0.323	.008	.005	3	1
CCRCC	C20orf27 →	-0.258	-0.308	.002	.002	3	1
CCRCC	PGRMC1 →	+0.600	+0.326	<.001	.007	3	1
CCRCC	GIPR →	-0.619	-0.493	<.001	<.001	3	1
CCRCC	SALL1 →	+0.896	+0.380	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,041 associations by consensus.

DEPDC7 vs MAPK1 — CCRCC

Explore this scatter interactively →