DEPDC5

Across TCGA cell cohorts, DEPDC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,421 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DEPDC5-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with DEPDC5 in more than 16 cancer types. Because this analysis shows association rather than direction, both DEPDC5-to-partner and partner-to-DEPDC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by DEPDC5-low versus DEPDC5-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC5→partner) and Y-score (partner→DEPDC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of chromosome condensation →	+0.160	+0.570	<.001	.001	3	17
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.150	+0.695	<.001	<.001	3	14
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.150	+0.695	<.001	<.001	3	14
LARGE_INTESTINE	Microtubule organizing center organization →	+0.074	+0.814	<.001	<.001	3	14
LARGE_INTESTINE	Mitotic DNA damage checkpoint signaling →	+0.087	+0.895	<.001	<.001	3	14
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.096	+0.501	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,421 associations by consensus.

Negative regulation of chromosome condensation by DEPDC5 expression — PANCREAS

Explore this box plot interactively →