DEPDC1P1

Across TCGA pan-cancer cohorts, DEPDC1P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of DEPDC1P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where DEPDC1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DEPDC1P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, UCEC, and LUSC are the cancer types where DEPDC1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DEPDC1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.019	.014	4	view →
UCEC	All	All	+0.033	.012	2	view →
LUSC	Male	All	+0.016	.001	2	view →
THCA	Female	All	−0.008	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

DEPDC1P1–BRCA

Open the BRCA breakdown →