DENR

Across TCGA patient cohorts, DENR RNA expression is significantly associated with the protein abundance of many other proteins, with 18,665 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DENR-associated proteins across cancer lineages are DDX21, SRSF9, and PURA. Each is linked with DENR in more than 7 cancer types. Because this analysis shows association rather than direction, both DENR-to-partner and partner-to-DENR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DENR versus DDX21 in LUAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DENR→partner) and Y-score (partner→DENR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DDX21 →	+0.425	+0.344	<.001	<.001	3	8
PDAC	SRSF9 →	+0.405	+0.372	<.001	<.001	3	8
OV	PURA →	-0.427	-0.404	.001	<.001	3	7
PDAC	RCL1 →	+0.314	+0.385	<.001	<.001	3	7
LUAD	PRKDC →	+0.278	+0.421	<.001	.001	3	7
LUAD	NAA25 →	+0.314	+0.468	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,665 associations by consensus.

DENR vs DDX21 — LUAD

Explore this scatter interactively →