DENR

Across TCGA patient cohorts, DENR protein abundance is significantly associated with the RNA expression of many other genes, with 13,112 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DENR-associated genes across cancer lineages are CXCR2, CD69, and ADGRE3. Each is linked with DENR in more than 5 cancer types. Because this analysis shows association rather than direction, both DENR-to-partner and partner-to-DENR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DENR versus CXCR2 in LSCC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DENR→partner) and Y-score (partner→DENR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CXCR2 →	-1.085	-0.267	<.001	<.001	3	6
OV	CD69 →	-1.128	-0.334	.001	.007	3	5
LSCC	ADGRE3 →	-0.554	-0.207	<.001	<.001	3	5
OV	FCGR3B →	-1.483	-0.436	<.001	<.001	3	5
UCEC	CXCR1 →	-0.940	-0.242	<.001	<.001	3	5
UCEC	CEACAM3 →	-0.668	-0.301	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,112 associations by consensus.

DENR vs CXCR2 — LSCC

Explore this scatter interactively →