DENND5A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DENND5A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,827 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DENND5A-associated GO terms across cancer lineages are Regulation of cell-substrate junction assembly, Response to oscillatory fluid shear stress, and Cellular response to oscillatory fluid shear stress. Each is linked with DENND5A in more than 12 cancer types. Because this analysis shows association rather than direction, both DENND5A-to-partner and partner-to-DENND5A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND5A→partner) and Y-score (partner→DENND5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONERegulation of cell-substrate junction assembly →+0.133+0.780.004<.001313
STOMACHResponse to oscillatory fluid shear stress →+0.144+2.278<.001<.001313
STOMACHCellular response to oscillatory fluid shear stress →+0.144+2.278<.001<.001313
STOMACHVascular endothelial cell response to oscillatory fluid shear stress →+0.144+2.278<.001<.001313
UPPER_AERODIGESTIVE_TRACTVesicle cargo loading →+0.115+1.320<.001<.001313
BONERegulation of focal adhesion assembly →+0.133+0.780.004<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,827 associations by consensus.

Exploration