DENND2A

Across TCGA patient cohorts, DENND2A RNA expression is significantly associated with the protein abundance of many other proteins, with 18,005 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DENND2A-associated proteins across cancer lineages are NES, NES_S768, and SSC5D. Each is linked with DENND2A in more than 8 cancer types. Because this analysis shows association rather than direction, both DENND2A-to-partner and partner-to-DENND2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DENND2A versus NES in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND2A→partner) and Y-score (partner→DENND2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NES →	+0.644	+0.827	<.001	<.001	3	9
BRCA	NES_S768 →	+0.593	+0.628	.009	.001	3	9
CCRCC	SSC5D →	+0.759	+0.685	<.001	<.001	3	8
UCEC	CAVIN1 →	+0.822	+0.854	<.001	<.001	3	8
CCRCC	DENND2A_S504 →	+1.155	+1.385	.002	.003	3	8
UCEC	PRKG1 →	+0.721	+0.763	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,005 associations by consensus.

DENND2A vs NES — UCEC

Explore this scatter interactively →