Across TCGA cell cohorts, DENND1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,106 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DENND1B-associated GO terms across cancer lineages are Vesicle budding from membrane, Post-Golgi vesicle-mediated transport, and Endoplasmic reticulum mannose trimming. Each is linked with DENND1B in more than 10 cancer types. Because this analysis shows association rather than direction, both DENND1B-to-partner and partner-to-DENND1B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND1B→partner) and Y-score (partner→DENND1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Vesicle budding from membrane →	+0.044	+0.474	.002	.001	3	11
OVARY	Post-Golgi vesicle-mediated transport →	+0.058	+0.772	.001	.004	3	10
BONE	Endoplasmic reticulum mannose trimming →	+0.126	+1.131	<.001	.002	3	10
LIVER	Golgi vesicle transport →	+0.064	+0.748	.007	.008	3	9
URINARY_TRACT	Membrane fission →	+0.058	+0.554	<.001	.003	3	9
PANCREAS	Regulation of endoplasmic reticulum tubular network organization →	+0.100	+0.733	.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,106 associations by consensus.

Exploration

DENND1B survival (RNA) · tumor vs normal (RNA) · all DENND1B data types