DELEC1

Across TCGA patient cohorts, DELEC1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DELEC1-associated genes across cancer lineages are RN7SL680P, C2orf83, and RNU6-751P. Each is linked with DELEC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DELEC1-to-partner and partner-to-DELEC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL680P grouped by DELEC1-low versus DELEC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DELEC1→partner) and Y-score (partner→DELEC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL680P →	+0.227	+5.634	<.001	.001	3	1
SKCM	C2orf83 →	+0.047	+3.856	.001	.008	3	1
LUAD	RNU6-751P →	+0.427	+7.930	<.001	.008	3	1
SKCM	MRPS21P8 →	+0.147	+4.385	<.001	.008	3	1
COAD	MBD3L3 →	+0.129	+7.741	<.001	.009	3	1
COAD	MIR1263 →	+1.494	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

RN7SL680P by DELEC1 expression — SKCM

Explore this box plot interactively →