DELE1

Across TCGA patient cohorts, DELE1 protein abundance is significantly associated with the RNA expression of many other genes, with 664 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DELE1-associated genes across cancer lineages are PDGFRL, C1orf109, and OR1E2. Each is linked with DELE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DELE1-to-partner and partner-to-DELE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DELE1 versus PDGFRL in HNSC, with a Pearson correlation of -0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DELE1→partner) and Y-score (partner→DELE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PDGFRL →	-1.540	-0.912	<.001	.007	3	1
HNSC	C1orf109 →	+0.407	+0.690	.002	.008	3	1
HNSC	OR1E2 →	-0.172	-0.752	.003	.004	3	1
HNSC	KIAA0895 →	+1.582	+0.912	.004	.007	3	1
HNSC	DMRTA1 →	+2.296	+0.690	<.001	.008	3	1
HNSC	RNVU1-22 →	+2.293	+0.689	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 664 associations by consensus.

DELE1 vs PDGFRL — HNSC

Explore this scatter interactively →