DELE1

Across TCGA cell cohorts, DELE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,020 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DELE1-associated GO terms across cancer lineages are Cytosolic transport, mRNA alternative polyadenylation, and Viral translational termination-reinitiation. Each is linked with DELE1 in more than 12 cancer types. Because this analysis shows association rather than direction, both DELE1-to-partner and partner-to-DELE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by DELE1-low versus DELE1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DELE1→partner) and Y-score (partner→DELE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytosolic transport →	+0.066	+0.729	.002	.001	3	13
LARGE_INTESTINE	mRNA alternative polyadenylation →	+0.089	+0.723	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.115	+1.152	<.001	<.001	3	12
LARGE_INTESTINE	Endocytic recycling →	+0.062	+0.715	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.167	+1.253	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Metaphase/anaphase transition of mitotic cell cycle →	+0.159	+1.203	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,020 associations by consensus.

Cytosolic transport by DELE1 expression — BONE

Explore this box plot interactively →