DEK

Across TCGA patient cohorts, DEK protein abundance is significantly associated with the RNA expression of many other genes, with 19,947 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DEK-associated genes across cancer lineages are PPIH, RMI2, and VRK1. Each is linked with DEK in more than 7 cancer types. Because this analysis shows association rather than direction, both DEK-to-partner and partner-to-DEK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEK versus PPIH in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEK→partner) and Y-score (partner→DEK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPIH →	+0.479	+0.438	<.001	<.001	3	8
OV	RMI2 →	+0.786	+0.455	.002	.002	3	8
HNSC	VRK1 →	+0.708	+0.379	<.001	<.001	3	7
GBM	SP4 →	+0.620	+0.452	<.001	<.001	3	7
HNSC	RIOK1 →	+0.755	+0.266	.002	<.001	3	7
LSCC	USP21 →	+0.614	+0.305	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,947 associations by consensus.

DEK vs PPIH — LSCC

Explore this scatter interactively →