DEGS2

Across TCGA patient cohorts, DEGS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,848 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DEGS2-associated proteins across cancer lineages are PPP1R18_S224, NNMT, and RCN1. Each is linked with DEGS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DEGS2-to-partner and partner-to-DEGS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEGS2 versus PPP1R18_S224 in OV, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEGS2→partner) and Y-score (partner→DEGS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP1R18_S224 →	-0.722	-0.742	.002	.006	3	7
OV	NNMT →	-0.944	-0.870	<.001	.001	3	6
PDAC	RCN1 →	-0.423	-0.923	.003	.001	3	6
BRCA	CALU →	-0.521	-1.935	<.001	<.001	3	6
BRCA	ELAPOR1 →	+0.997	+2.363	<.001	<.001	3	6
BRCA	BSPRY →	+0.482	+1.187	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,848 associations by consensus.

DEGS2 vs PPP1R18_S224 — OV

Explore this scatter interactively →