DEGS2

Across TCGA cell cohorts, DEGS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,492 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DEGS2-associated GO terms across cancer lineages are Membrane bending, Regulation of fibrinolysis, and Fatty acid catabolic process. Each is linked with DEGS2 in more than 10 cancer types. Because this analysis shows association rather than direction, both DEGS2-to-partner and partner-to-DEGS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane bending grouped by DEGS2-low versus DEGS2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEGS2→partner) and Y-score (partner→DEGS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Membrane bending →	+0.223	+3.436	<.001	<.001	3	10
SOFT_TISSUE	Regulation of fibrinolysis →	-0.243	-0.175	.001	.002	2	11
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.081	+0.694	<.001	.006	3	9
OVARY	Dentinogenesis →	-1.595	-1.144	<.001	.003	3	8
STOMACH	Establishment of epithelial cell apical/basal polarity →	-0.212	-1.964	<.001	.001	2	9
BREAST	Peptidyl-lysine oxidation →	-1.475	-3.716	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,492 associations by consensus.

Membrane bending by DEGS2 expression — STOMACH

Explore this box plot interactively →