Across TCGA patient cohorts, DEFB136 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,346 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB136-associated GO terms across cancer lineages are Negative regulation of neuron projection development, Protein-containing complex disassembly, and Establishment of protein localization to membrane. Each is linked with DEFB136 in more than 10 cancer types. Because this analysis shows association rather than direction, both DEFB136-to-partner and partner-to-DEFB136 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB136→partner) and Y-score (partner→DEFB136) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of neuron projection development →	+0.054	+0.253	<.001	<.001	3	10
STAD	Protein-containing complex disassembly →	+0.076	+0.235	<.001	<.001	3	10
STAD	Establishment of protein localization to membrane →	+0.073	+0.202	<.001	<.001	3	10
STAD	Positive regulation of double-strand break repair →	+0.070	+0.204	<.001	<.001	3	10
STAD	Glucan metabolic process →	+0.066	+0.240	<.001	<.001	3	9
STAD	Positive regulation of binding →	+0.075	+0.215	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,346 associations by consensus.

Exploration

DEFB136 survival (RNA) · tumor vs normal (RNA) · all DEFB136 data types