Across TCGA patient cohorts, DEFB135 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,648 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB135-associated GO terms across cancer lineages are Protein depolymerization, Negative regulation of plasma membrane bounded cell projection assembly, and Regulation of protein depolymerization. Each is linked with DEFB135 in more than 6 cancer types. Because this analysis shows association rather than direction, both DEFB135-to-partner and partner-to-DEFB135 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB135→partner) and Y-score (partner→DEFB135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein depolymerization →	+0.066	+0.134	<.001	<.001	3	7
ESCA	Negative regulation of plasma membrane bounded cell projection assembly →	+0.065	+0.131	<.001	<.001	3	6
STAD	Regulation of protein depolymerization →	+0.070	+0.141	<.001	<.001	3	6
STAD	Positive regulation of cytoplasmic translational initiation →	+0.061	+0.129	<.001	<.001	3	6
STAD	Cytoplasmic translational initiation →	+0.091	+0.184	<.001	<.001	3	6
STAD	Protein-containing complex disassembly →	+0.083	+0.140	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,648 associations by consensus.

Exploration

DEFB135 survival (RNA) · tumor vs normal (RNA) · all DEFB135 data types