DEFB132

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DEFB132 RNA expression is significantly associated with the go_rna of many other GO terms, with 366 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DEFB132-associated GO terms across cancer lineages are Cardiac septum morphogenesis, Acrosomal vesicle exocytosis, and Macrophage proliferation. Each is linked with DEFB132 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB132-to-partner and partner-to-DEFB132 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB132→partner) and Y-score (partner→DEFB132) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTCardiac septum morphogenesis →-0.072-0.209<.001.00532
BREASTAcrosomal vesicle exocytosis →+0.912+0.278<.001.00732
BREASTMacrophage proliferation →+0.195+0.225.006.00232
BREASTMicroglial cell proliferation →+0.195+0.225.006.00232
BLOOD_LeukemiaAtrial cardiac muscle cell action potential →-1.057-0.004.002.00832
BLOOD_LeukemiaAtrial cardiac muscle cell to AV node cell signaling →-1.057-0.004.002.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 366 associations by consensus.

Exploration