DEFB131C

RNA expression — cross-omics
Cross-omicsRNA → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DEFB131C RNA expression is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DEFB131C-associated genes across cancer lineages are Mesangial cells, Platelets, and CD4+ T-cells. Each is linked with DEFB131C in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB131C-to-partner and partner-to-DEFB131C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by DEFB131C-low versus DEFB131C-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB131C→partner) and Y-score (partner→DEFB131C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMesangial cells →+0.017+0.010.006.02031
SKCMPlatelets →+0.076+0.009<.001.00431
SKCMCD4+ T-cells →+0.026+0.041<.001<.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Mesangial cells by DEFB131C expression — SKCM

Box plot of Mesangial cells in DEFB131C-low vs DEFB131C-high samples in SKCM.

Explore this box plot interactively →

Exploration