DEFB123

Across TCGA patient cohorts, DEFB123 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,737 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB123-associated GO terms across cancer lineages are Aerobic respiration, tRNA metabolic process, and RNA modification. Each is linked with DEFB123 in more than 12 cancer types. Because this analysis shows association rather than direction, both DEFB123-to-partner and partner-to-DEFB123 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by DEFB123-low versus DEFB123-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB123→partner) and Y-score (partner→DEFB123) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Aerobic respiration →	+0.089	+0.310	<.001	<.001	3	13
STAD	tRNA metabolic process →	+0.070	+0.283	<.001	<.001	3	12
STAD	RNA modification →	+0.066	+0.274	<.001	<.001	3	11
STAD	Regulation of double-strand break repair via homologous recombination →	+0.066	+0.276	<.001	<.001	3	11
STAD	rRNA modification →	+0.063	+0.291	<.001	<.001	3	11
ESCA	Protein-containing complex localization →	+0.054	+0.170	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,737 associations by consensus.

Aerobic respiration by DEFB123 expression — STAD

Explore this box plot interactively →