DEFB117

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DEFB117 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,278 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB117-associated GO terms across cancer lineages are Microtubule-based transport, Positive regulation of cell cycle G2/M phase transition, and Regulation of cyclin-dependent protein kinase activity. Each is linked with DEFB117 in more than 8 cancer types. Because this analysis shows association rather than direction, both DEFB117-to-partner and partner-to-DEFB117 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB117→partner) and Y-score (partner→DEFB117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADMicrotubule-based transport →+0.070+0.146<.001<.00139
STADPositive regulation of cell cycle G2/M phase transition →+0.086+0.170<.001<.00139
STADRegulation of cyclin-dependent protein kinase activity →+0.088+0.183<.001<.00139
STADRegulation of centrosome cycle →+0.098+0.188<.001<.00139
STADNucleus organization →+0.108+0.183<.001<.00139
STADNuclear envelope organization →+0.113+0.159<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,278 associations by consensus.

Exploration