DEFB116

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DEFB116 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,160 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB116-associated GO terms across cancer lineages are Regulation of protein ubiquitination, Regulation of proteolysis involved in protein catabolic process, and Regulation of neuron apoptotic process. Each is linked with DEFB116 in more than 9 cancer types. Because this analysis shows association rather than direction, both DEFB116-to-partner and partner-to-DEFB116 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB116→partner) and Y-score (partner→DEFB116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRegulation of protein ubiquitination →+0.082+0.244<.001<.001310
STADRegulation of proteolysis involved in protein catabolic process →+0.080+0.221<.001<.00139
STADRegulation of neuron apoptotic process →+0.063+0.240<.001<.00139
STADPositive regulation of translation →+0.083+0.216<.001<.00139
STADRibose phosphate biosynthetic process →+0.079+0.198<.001<.00139
STADDNA-templated transcription elongation →+0.088+0.245<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,160 associations by consensus.

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