Across TCGA cell cohorts, DEFB116 RNA expression is significantly associated with the RNA expression of many other genes, with 410 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible DEFB116-associated genes across cancer lineages are IFNA14, OR5V1, and OR2T11. Each is linked with DEFB116 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB116-to-partner and partner-to-DEFB116 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB116→partner) and Y-score (partner→DEFB116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	IFNA14 →	+0.175	+0.172	<.001	.001	3	2
LUNG_NSCLC_LUSC	OR5V1 →	+0.153	+0.172	<.001	.001	3	2
OVARY	OR2T11 →	+0.076	+0.043	<.001	.008	3	2
LUNG_NSCLC_LUSC	PRAMEF18 →	+0.164	+0.230	<.001	<.001	3	2
LUNG_NSCLC_LUSC	OR8B4 →	+0.115	+0.345	<.001	<.001	3	2
LUNG_NSCLC_LUSC	GPR101 →	+0.053	+0.170	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 410 associations by consensus.

Exploration

DEFB116 survival (RNA) · tumor vs normal (RNA) · all DEFB116 data types