DEFB114

Across TCGA pan-cancer cohorts, DEFB114 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated DEFB114 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DEFB114 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DEFB114 expression acts as an unfavorable survival marker.

COAD are the cancer types where DEFB114 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.163	0.802	<.001	48	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

DEFB114–COAD (OS)

Open the COAD breakdown →