DEFB114

Across TCGA patient cohorts, DEFB114 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,632 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB114-associated GO terms across cancer lineages are Establishment or maintenance of monopolar cell polarity, Peptidyl-lysine methylation, and Hematopoietic or lymphoid organ development. Each is linked with DEFB114 in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB114-to-partner and partner-to-DEFB114 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of monopolar cell polarity grouped by DEFB114-low versus DEFB114-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB114→partner) and Y-score (partner→DEFB114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Establishment or maintenance of monopolar cell polarity →	+0.135	+0.063	<.001	.006	2	3
STAD	Peptidyl-lysine methylation →	+0.159	+0.051	<.001	.002	3	2
STAD	Hematopoietic or lymphoid organ development →	+0.159	+0.050	<.001	.001	3	2
STAD	Regulation of smooth muscle cell differentiation →	+0.132	+0.067	<.001	.006	3	2
STAD	Trachea development →	+0.203	+0.059	<.001	<.001	3	2
STAD	Positive regulation of cardiac epithelial to mesenchymal transition →	+0.174	+0.043	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,632 associations by consensus.

Establishment or maintenance of monopolar cell polarity by DEFB114 expression — STAD

Explore this box plot interactively →