Across TCGA patient cohorts, DEFB113 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,496 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB113-associated GO terms across cancer lineages are Regulation of reproductive process, Mitochondrial gene expression, and Positive regulation of calcium ion transmembrane transport. Each is linked with DEFB113 in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB113-to-partner and partner-to-DEFB113 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB113→partner) and Y-score (partner→DEFB113) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of reproductive process →	+0.110	+0.080	<.001	<.001	3	3
STAD	Mitochondrial gene expression →	+0.243	+0.050	<.001	<.001	3	3
STAD	Positive regulation of calcium ion transmembrane transport →	+0.080	+0.079	<.001	.001	3	3
STAD	Mitochondrial translation →	+0.249	+0.098	<.001	<.001	3	3
STAD	Oxidative phosphorylation →	+0.266	+0.044	<.001	.001	3	3
STAD	Regulation of mitotic cell cycle spindle assembly checkpoint →	+0.169	+0.046	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,496 associations by consensus.

Exploration

DEFB113 survival (RNA) · tumor vs normal (RNA) · all DEFB113 data types