DEFB107A

associated omics data
Gene

Q-omics provides the consensus-scored DEFB107A profile across patient tissues and cancer cell-line models. DEFB107A expression is associated with patient survival in 2 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, DEFB107A RNA expression shows 5,973 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight STAD as cancer lineages where DEFB107A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes DEFB107A survival associations across molecular data types. DEFB107A RNA expression shows survival associations in the most cancer types (2), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
DEFB107A data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier2STAD (63)view →
MutationKaplan–Meier1COAD (27)view →
This table ranks reproducible DEFB107A RNA expression–survival associations across cancer types. High DEFB107A expression shows unfavorable associations in STAD, but favorable associations in ESCA. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify STAD as the clearest survival context for DEFB107A RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileIV0.0830.379.00163view →
ESCADFSTertileIII,IV0.8500.282.01815view →
Pink = unfavorable, green = favorable. all 2 lineages →

DEFB107A-STAD (DFS)

Kaplan–Meier survival curve for DEFB107A RNA expression in STAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB107A in patient tissues and cancer cell lines. In patient samples, DEFB107A shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
Function (RNA)5,973STAD (5924)view →
RNA1,695STAD (1154)view →