DEFB104A

Across TCGA patient cohorts, DEFB104A RNA expression is significantly associated with the go_rna of many other GO terms, with 645 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible DEFB104A-associated GO terms across cancer lineages are Establishment of skin barrier, Epidermal cell differentiation, and Positive regulation of keratinocyte proliferation. Each is linked with DEFB104A in more than 3 cancer types. Because this analysis shows association rather than direction, both DEFB104A-to-partner and partner-to-DEFB104A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of skin barrier grouped by DEFB104A-low versus DEFB104A-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB104A→partner) and Y-score (partner→DEFB104A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Establishment of skin barrier →	+0.108	+0.068	<.001	.002	3	3
ESCA	Epidermal cell differentiation →	+0.090	+0.070	<.001	.001	3	3
ESCA	Positive regulation of keratinocyte proliferation →	+0.176	+0.065	<.001	.003	3	3
ESCA	Antibacterial peptide production →	+0.157	+0.107	<.001	.001	3	3
ESCA	Keratinocyte differentiation →	+0.094	+0.122	<.001	.003	3	3
ESCA	Keratinization →	+0.202	+0.128	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 645 associations by consensus.

Establishment of skin barrier by DEFB104A expression — ESCA

Explore this box plot interactively →