DEFB104A

Across TCGA cell cohorts, DEFB104A RNA expression is significantly associated with the mutation status of many other genes, with 4 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible DEFB104A-associated genes across cancer lineages are GGA1, PLCL1, and ANKLE2. Each is linked with DEFB104A in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB104A-to-partner and partner-to-DEFB104A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGA1 grouped by DEFB104A-low versus DEFB104A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB104A→partner) and Y-score (partner→DEFB104A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	GGA1 →	+4.357	+0.152	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	PLCL1 →	+4.357	+0.152	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ANKLE2 →	+5.357	+0.203	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	COPG1 →	+4.357	+0.152	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GGA1 by DEFB104A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →