DEFB103A

Across TCGA patient cohorts, DEFB103A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,125 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DEFB103A-associated GO terms across cancer lineages are Urea transport, Antimicrobial peptide production, and Antibacterial peptide production. Each is linked with DEFB103A in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB103A-to-partner and partner-to-DEFB103A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urea transport grouped by DEFB103A-low versus DEFB103A-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB103A→partner) and Y-score (partner→DEFB103A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Urea transport →	+0.113	+0.094	<.001	<.001	3	3
HNSC	Antimicrobial peptide production →	+0.132	+0.104	<.001	<.001	3	3
HNSC	Antibacterial peptide production →	+0.128	+0.110	<.001	<.001	3	3
ESCA	Purine-containing compound catabolic process →	-0.031	-0.463	<.001	.004	3	2
ESCA	Intracellular sphingolipid homeostasis →	-0.052	-0.556	<.001	.004	3	2
ESCA	Regulation of DNA methylation-dependent heterochromatin formation →	-0.040	-0.467	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,125 associations by consensus.

Urea transport by DEFB103A expression — HNSC

Explore this box plot interactively →