DEFB1

Across TCGA cell cohorts, DEFB1 RNA expression is significantly associated with the RNA expression of many other genes, with 6,518 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DEFB1-associated genes across cancer lineages are SLPI, LRG1, and PSIP1. Each is linked with DEFB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both DEFB1-to-partner and partner-to-DEFB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEFB1 versus SLPI in PANCREAS, with a Pearson correlation of 0.54.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB1→partner) and Y-score (partner→DEFB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	SLPI →	+4.363	+3.893	<.001	<.001	3	9
LIVER	LRG1 →	+3.561	+4.317	<.001	<.001	3	7
URINARY_TRACT	PSIP1 →	-2.473	-2.951	.002	.002	3	6
LIVER	CEBPA →	+3.343	+3.493	<.001	<.001	3	6
URINARY_TRACT	S100P →	+6.208	+2.342	<.001	<.001	3	5
URINARY_TRACT	ADAMTS6 →	-1.701	-1.971	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,518 associations by consensus.

DEFB1 vs SLPI — PANCREAS

Explore this scatter interactively →