Across TCGA patient cohorts, DEFA8P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,347 significant associations in total. THYM shows the largest number of these associations.

The most reproducible DEFA8P-associated GO terms across cancer lineages are Disruption of plasma membrane integrity in another organism, Ribosomal small subunit assembly, and Ribosome assembly. Each is linked with DEFA8P in more than 7 cancer types. Because this analysis shows association rather than direction, both DEFA8P-to-partner and partner-to-DEFA8P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFA8P→partner) and Y-score (partner→DEFA8P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Disruption of plasma membrane integrity in another organism →	+1.154	+1.047	<.001	<.001	3	8
STAD	Ribosomal small subunit assembly →	+0.058	+0.221	<.001	<.001	3	7
STAD	Ribosome assembly →	+0.065	+0.133	<.001	<.001	3	7
STAD	NADH dehydrogenase complex assembly →	+0.069	+0.170	<.001	<.001	2	8
SKCM	ATP synthesis coupled electron transport →	+0.037	+0.013	<.001	.002	3	7
STAD	Positive regulation of DNA biosynthetic process →	+0.063	+0.148	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,347 associations by consensus.

Exploration

DEFA8P survival (RNA) · tumor vs normal (RNA) · all DEFA8P data types