DEDD2

Across TCGA cell cohorts, DEDD2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,494 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DEDD2-associated genes across cancer lineages are CYP2U1, IL17RB, and RAG1. Each is linked with DEDD2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DEDD2-to-partner and partner-to-DEDD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEDD2 versus CYP2U1 in SKIN, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEDD2→partner) and Y-score (partner→DEDD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CYP2U1 →	-2.192	-1.322	.001	.004	2	6
SKIN	IL17RB →	-0.680	-1.692	.003	.009	3	5
CNS	RAG1 →	+0.340	+0.823	.003	.003	3	4
SKIN	ZNF445 →	-0.725	-1.165	.008	.004	3	4
BLOOD_Lymphoma	PDP2 →	+0.818	+1.264	.002	.006	3	4
CNS	CLIP3 →	-2.178	-0.924	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,494 associations by consensus.

DEDD2 vs CYP2U1 — SKIN

Explore this scatter interactively →