DEDD2

Across TCGA cell cohorts, DEDD2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,042 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DEDD2-associated GO terms across cancer lineages are Nucleoside diphosphate biosynthetic process, Negative regulation of satellite cell differentiation, and Negative regulation of vascular endothelial growth factor signaling pathway. Each is linked with DEDD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DEDD2-to-partner and partner-to-DEDD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside diphosphate biosynthetic process grouped by DEDD2-low versus DEDD2-high in SKIN.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEDD2→partner) and Y-score (partner→DEDD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Nucleoside diphosphate biosynthetic process →	+0.205	+1.767	.003	.001	3	4
STOMACH	Negative regulation of satellite cell differentiation →	+0.231	+1.405	.006	<.001	3	4
PANCREAS	Negative regulation of vascular endothelial growth factor signaling pathway →	-0.284	-1.452	.002	.001	3	4
BREAST	Positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell →	-0.231	-1.145	.001	.001	3	4
OVARY	Arginine metabolic process →	+0.152	+1.254	.004	.004	3	3
OVARY	Centromeric sister chromatid cohesion →	+0.158	+1.134	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,042 associations by consensus.

Nucleoside diphosphate biosynthetic process by DEDD2 expression — SKIN

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