DEDD

Across TCGA patient cohorts, DEDD RNA expression is significantly associated with the protein abundance of many other proteins, with 14,970 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DEDD-associated proteins across cancer lineages are GATAD2B, POGK, and RPRD2. Each is linked with DEDD in more than 7 cancer types. Because this analysis shows association rather than direction, both DEDD-to-partner and partner-to-DEDD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEDD versus GATAD2B in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEDD→partner) and Y-score (partner→DEDD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GATAD2B →	+0.309	+0.323	<.001	<.001	3	8
LSCC	POGK →	+0.405	+0.460	<.001	<.001	3	7
LSCC	RPRD2 →	+0.320	+0.416	<.001	<.001	3	7
GBM	C1orf35 →	+0.454	+0.303	<.001	<.001	3	7
LSCC	PRCC_S267 →	+0.392	+0.391	<.001	<.001	3	6
GBM	PRPF4 →	+0.287	+0.313	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,970 associations by consensus.

DEDD vs GATAD2B — GBM

Explore this scatter interactively →