DECR2

Across TCGA cell cohorts, DECR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,279 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DECR2-associated GO terms across cancer lineages are Fatty acid beta-oxidation, Fatty acid catabolic process, and Lipid oxidation. Each is linked with DECR2 in more than 15 cancer types. Because this analysis shows association rather than direction, both DECR2-to-partner and partner-to-DECR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid beta-oxidation grouped by DECR2-low versus DECR2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DECR2→partner) and Y-score (partner→DECR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Fatty acid beta-oxidation →	+0.119	+1.013	<.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.082	+1.037	.002	.004	3	14
LIVER	Lipid oxidation →	+0.087	+1.131	.001	.001	3	14
LIVER	Fatty acid oxidation →	+0.092	+1.063	<.001	.001	3	14
BONE	Pre-mRNA catabolic process →	+0.224	+1.158	<.001	<.001	3	13
BLOOD_Leukemia	Calcium-independent cell-matrix adhesion →	+0.179	+0.680	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,279 associations by consensus.

Fatty acid beta-oxidation by DECR2 expression — LIVER

Explore this box plot interactively →