DECR1

Across TCGA pan-cancer cohorts, DECR1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DECR1 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DECR1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DECR1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, CCRCC, and LUAD are the cancer types where DECR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.891	.027	54	view →
CCRCC	DFS	Tertile	III,IV	0.343	0.674	.020	19	view →
LUAD	OS	Quartile	All	0.694	0.930	.006	12	view →
HNSC	DFS	Tertile	IV	0.594	0.822	.024	10	view →
LSCC	DFS	Median	III,IV	0.984	0.583	.031	2	view →
GBM	OS	Quartile	All	1.000	0.806	.017	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DECR1–COAD (DFS)

Open the COAD breakdown →