DEAF1

Across TCGA patient cohorts, DEAF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,507 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DEAF1-associated proteins across cancer lineages are GTF2I, MLKL_S106, and ARFGEF2. Each is linked with DEAF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DEAF1-to-partner and partner-to-DEAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEAF1 versus GTF2I in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEAF1→partner) and Y-score (partner→DEAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GTF2I →	+0.438	+0.511	<.001	<.001	3	4
GBM	MLKL_S106 →	-1.667	-0.725	<.001	<.001	3	4
LSCC	ARFGEF2 →	-0.214	-0.350	<.001	<.001	3	4
BRCA	ARFIP2 →	+0.559	+0.815	<.001	<.001	3	4
OV	VEZF1 →	+0.410	+0.464	<.001	.001	3	4
COAD	ACSL5 →	-0.820	-0.575	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,507 associations by consensus.

DEAF1 vs GTF2I — GBM

Explore this scatter interactively →