DEAF1

Across TCGA patient cohorts, DEAF1 mutation is significantly associated with the RNA expression of many other genes, with 2,842 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEAF1-associated genes across cancer lineages are LINC01830, MIR449B, and RANBP1P1. Each is linked with DEAF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DEAF1-to-partner and partner-to-DEAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01830 grouped by DEAF1-low versus DEAF1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEAF1→partner) and Y-score (partner→DEAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01830 →	+0.057	+3.614	<.001	.002	3	3
HNSC	MIR449B →	+0.323	+7.954	<.001	.008	3	3
UCEC	RANBP1P1 →	+0.478	+2.928	<.001	<.001	3	3
LUSC	PSMD12P1 →	+0.222	+3.868	<.001	.001	3	3
LUSC	RNU2-33P →	+0.625	+3.951	<.001	.001	3	3
LUSC	GAPDHP56 →	+0.129	+3.792	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,842 associations by consensus.

LINC01830 by DEAF1 expression — SKCM

Explore this box plot interactively →