DEAF1

Across TCGA cell cohorts, DEAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,681 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DEAF1-associated GO terms across cancer lineages are Methylglyoxal catabolic process, Cellular detoxification of methylglyoxal, and Behavioral defense response. Each is linked with DEAF1 in more than 14 cancer types. Because this analysis shows association rather than direction, both DEAF1-to-partner and partner-to-DEAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylglyoxal catabolic process grouped by DEAF1-low versus DEAF1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEAF1→partner) and Y-score (partner→DEAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Methylglyoxal catabolic process →	+0.218	+1.154	<.001	<.001	3	15
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.191	+1.222	<.001	<.001	3	14
SKIN	Behavioral defense response →	+0.248	+0.790	.006	<.001	3	14
OESOPHAGUS	Response to methylglyoxal →	+0.191	+1.222	<.001	<.001	3	14
OESOPHAGUS	Methylglyoxal metabolic process →	+0.136	+0.825	<.001	.003	3	14
OESOPHAGUS	Cellular response to methylglyoxal →	+0.191	+1.222	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,681 associations by consensus.

Methylglyoxal catabolic process by DEAF1 expression — OESOPHAGUS

Explore this box plot interactively →